• A broad theme shows infection control and prophylaxis spanning community and hospital settings: prevention of streptococcal infections, control of bacterial causes of rheumatic disease, and hospital infection prevention as a core preventive strategy across the period, evidenced by works on streptococcal infection control, rheumatic fever prevention, and hospital infection causes/prevention [1], [4], [7], [8], [10].

• Chemical and pharmacological prophylaxis undergirds preventive medicine, highlighting chemical prevention of cardiac necroses, sulfamethoxypyrridazine use to prevent streptococcal infections, and prophylactic nitrofurantoin in urinary infection prevention, as well as gamma-globulin strategies in hepatitis prevention [3], [5], [14], [16].

• Rheumatic fever prevention/recurrence management emerges as a central, concerted research objective, with multiple studies focusing on treatment of streptococcal infections, recurrence prevention, and public health implications for rheumatic fever and rheumatic heart disease [2], [4], [6], [7], [18], [20].

• Public health/epidemiology and health education form the backbone of preventive medicine, with emphasis on epidemiology of health, community preventive medicine, TB prevention/BCG, and health policy commentary illustrating population-level preventive thinking [7], [8], [9], [11], [17].

• Clinical/hospital preventive care in perioperative and inpatient settings reveals targeted prevention—postoperative atelectasis, hospital infection prevention, and prophylaxis of transfusion reactions—demonstrating clinical preventive workflows beyond public health [10], [12], [13].